The results of paternity DNA testing are based upon statistical calculations of probability.
These calculations can be done in straightforward cases comprising an alleged father, a mother and child (trio) or in complex cases in which the alleged father is absent or deceased, so that information from his first degree relatives must be analyzed to reconstitute his genotypes.
These probability calculations are carried out using local population allele frequencies, which are continually updated as new unrelated individuals are added to the database as testing is carried out.
The GenomiCalc software, which allows the genotype data to be inputted manually or be uploaded using text files exported by the DNA sequencer, performs the probability calculations rapidly, leading to high probabilities of paternity provided that sufficient genotype data has been provided.
The GenomiCalc software can calculate all complex cases, in which the alleged father is absent.
The software interface is very simple, allowing lay persons with little knowledge of statistical genetics to do their own calculations. This applies to lawyers and judges who can check or confirm the calculations presented by any laboratory, especially because the genetic loci used in testing are now almost the same worldwide.
By using our software the following configurations can be analyzed:
 Duos: the probability of paternity or maternity is calculated using the genotype information of one alleged parent and the child.
 Trios: the probability of paternity is calculated using the genotype information of the alleged father, the mother and the child.
 Absent/deceased alleged father: the probability of paternity is calculated using the genotype information of first degree relatives of the alleged father, the child with or without the mother.
It is important to emphasize that the value of the final probability obtained is directly related to the number of participating individuals and to how closely related they are to the alleged father.
To see how easy it is to do the paternity calculation, click on the link tutorial.
Further queries may be answered by
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or by telephoning 55 11 32881188.
